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Dorsal lamellar keratoplasty (Literature review)


Penetrating keratoplasty is the only treatment for Fuchs’ endothelial dystrophy at those stages where there are grave irreversible changes in the stroma. However, in the earlier stages of the disease, selective replacement of the rear layer of the cornea is the most reasonable, pathogenetically justified and safe way to restore corneal transparency and improve visual function. The article provides an overview of the literature on the posterior lamellar keratoplasty. We describe the historical aspects and the modern state of the problem, discussed currently existing types of posterior lamellar keratoplasty, problems and shortcomings of these operations, the challenges facing the researchers at the present stage.


Fuchs’ endothelial dystrophy; posterior lamellar keratoplasty; descemet’s stripping automated endothelial keratoplasty; DSAEK; DMEK

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1. Sugar A., Sugar J.Techniques in pen-etrating keratoplasty: a quarter centry of development. Cornea, 2000, vol. 19, no. 5, pp. 603-610. 2. Kopaeva V.G., Leykina S.L., Yudova N.N. Konstruktsiya trepana i ee vliyanie na sostoyanie skvoznogo transplantata rogovitsy. Oftalmologicheskii Zhurnal – Journal of Ophthalmology, 1987, no. 6, p. 365. 3. Azar D.T., Jain S. Microkeratome-assisted posterior keratoplasty. J. Cataract Refract. Surg., 2002, no. 28 (5), pp. 732-733. 4. Perez V.L., Colby K.A., Azar D.T. Epithelial ingrowth in the flap-graft interface after microkeratomeassisted posterior penetrating keratoplasty. J. Cataract Refract. Surg., 2003, no. 29 (11), pp. 2225-2228. 5. Pirouzmanesh A., Herretes S., Reyes J.M. et al. Modified microkeratome-assisted posterior lamellar keratoplasty using a tissue adhesive. Arch. Ophthalmol., 2006, vol. 124, pp. 210-214. 6. Nuijts R. Exciting times for corneal surgeons. Eurotimes, 2009, vol. 14 (4). 7. Tillet C.W. Posterior lamellar keratoplasty. Am. J. Ophthalmol., 1956, vol. 41, no. 3, pp. 530-533. 8. Barraquer J.I. Lamellar keratoplasty (special techniques). Ann. Ophthalmol., 1972, vol. 4, pp. 437-469. 9. Volkov V.V., Dronov M.M. K razrabotke khirurgicheskogo metoda lecheniya endotelial'no-epitelial'noy distrofii rogovitsy. 1 s"ezd oftal'mologov respublik Zakavkaz'ya. Sukhumi, 1976. 10. Boyko A.V. Zadnyaya chastichnaya posloynaya keratoplastika pri posttravmaticheskikh izmeneniyakh perednego otrezka. Avtoreferat dissertatsii ... kandidata meditsinskikh nauk. Moscow, 1978. 20 p. 11. Gundorova R.A., Boyko A.V. Peresadka zadnikh sloev rogovitsy pri posttravmaticheskom vrastanii epiteliya. Materialy 3 nauchnoy konferentsii oftal'mologov Gruzii. Tbilisi, 1974, pp. 241-274. 12. Mamikonyan V.R., Trufanov S.V. Avtomatizirovannaya zadnyaya posloynaya keratoplastika v lechenii bulleznoy keratopatii. Byulleten' SO RAMN – The Bulletin of Siberian Branch of Russian Academy of Medical Sciences, 2009, no. 4, pp. 37-39. 13. Busin M., Arffa R.C., Sebastiani A. Endokeratoplasty as an alternative to penetrating keratoplasty for the surgical treatment of diseased endothelium: initial results. Ophthalmology, 2000, vol. 107, no. 11, pp. 20770-2082. 14. Melles G.R.J., Egging F.A., Lander F. et al. A surgical technique for posterior lamellar keratoplasty. Cornea, 1998, vol. 17, no. 6, pp. 618-626. 15. Melles G.R., Binder P.S., Anderson J.A. Variation in healing throughout the depth of long-term, unsutured, corneal wounds in human autopsy specimens and monkeys. Arch. Ophthalmol., 1994, vol. 112, no. 1, pp. 100-109. 16. Melles G.R., Binder P.S. Wound healing in sutured and unsutured corneal wound. Arch. Ophthalmol., 1990, vol. 108, pp. 1460-1469. 17. Melles G.R., Lander F., Nieuwendaal C.P. The future of lamellar keratoplasty. Curr. Opin. Ophthalmol., 1999, vol. 10, pp. 253-259. 18. Terry M.A. Deep Lamellar Endothelial Keratoplasty a new surgical cure for bullous keratopathy following cataract surgery. Cataract Refract. Surg. Today, 2004, vol. 4, pp. 20-24. 19. Terry M.A., Ousley P.J. Deep Lamellar Endothelial Keratoplasty (DLEK): visual acuity, astigmatism, end endothelial survival in a large prospective series. Ophtalmology, 2005, vol. 112, no. 9, pp. 1541-1549. 20. Terry M.A., Ousley P.J. Small-incision deep lamellar endothelial keratoplasty (DLEK): six month results in the first prospective clinical study. Cornea, 2005, vol. 24, no. 1, pp. 59-65. 21. Melles G.R., Wijdb R.H., Nieuwendaal C.P. A technique to excise the Descemet’s membrane from ar ecipient cornea (descemetorhexis). Cornea, 2004, vol. 23, pp. 286-288. 22. Terry M.A., Hoar K.I., Wall J., Ousley P. Histology of dislocations in endothelial keratoplasty (DSEK and DLEK): a laboratory-based, surgical solution to dislocation in 100 consecutive DSEK cases. Cornea, 2006, vol. 25, no. 8, pp. 926-932. 23. Armour R.L., Wilson D.J., Ousley P.J. et al. Deep lamellar endothelial keratoplasty (DLEK): How thick and uniform is the manual stromal dissection and does it affect vision? Invest. Ophtalmol. Vis. Sci., 2004, vol. 45, abstract 2898. 24. Gorovoy M. Descemet stripping automated endothelial keratoplasty. Cornea, 2006, vol. 25, no. 8, pp. 886-889. 25. Bursin M., Bhatt P.R., Scorcia V.A. Modified technique for Descemet membrane stripping automated endothelial keratoplasty to minimize endothelial cell loss. Arch. Ophthalmol., 2008, vol. 126, pp. 1133-1137. 26. Malyugin B.E., Moroz Z.I., Borzenok S.A., Drozdov I.V., Ayba E.E., Pashtaev A.N. Pervyy opyt i klinicheskie rezul'taty zadney avtomatizirovannoy posloynoy keratoplastiki (ZAPK) s ispol'zovaniem predvaritel'no vykroennykh konservirovannykh ul'tratonkikh rogovichnykh transplantatov. Oftal'mokhirurgiya – The Fyodorov Journal of Ophthalmic Surgery,2013, no. 3, pp. 12-16. 27. Melles G.R., Lander F., Rieveld F. Transplantation of Descemet’s membrane carrying viable endothelium through a small scleral incision. Cornea, 2002, vol. 21, no. 4, pp. 415-418. 28. Melles G.R., Ong T.S., Ververs B., van der Wees J. Descemet membrane endothelial keratoplasty (DMEK). Cornea, 2006, vol. 25, no. 8, pp. 987-990. 29. Dapena I., Moutsouris K., Melles G. Endothelial cell density after Descemet membrane endothelial keratoplasty (DMEK): 1-2 years follow-up. 27 Congress of the ESCRS. Abstracts Online, Barcelona, 2009. 30. Oganesyan O.G., Gundorova R.A., Vorob'eva M.A. Pervyy opyt transplantatsii izolirovannoy destsemetovoy membrany. Oftalmologicheskii Zhurnal – Journal of Ophthalmology, 2008, no. 9, pp. 40-43. 31. Oganesyan O.G., Neroev V.V., Gundorova R.A., Smetanina M.A., Danilova D.Yu. Mikroinvazivnaya destsemetoplastika. Analiz predvaritel'nykh rezul'tatov pervykh 20 sluchaev. Oftal'mokhirurgiya – The Fyodorov Journal of Ophthalmic Surgery, 2010, vol. 7, no. 2, pp. 20-25. 32. Seitz B., Langenbucber A., Hofmann-Rummelt C., Schlotzer-Schrebardt U., Naumann G.O. Non-mechanical posterior lamellar keratoplasty using the femtosecond laser (femto-PLAK) for corneal endothelial decompensation. Am. J. Ophtalmol., 2003, vol. 136, pp. 769-772. 33. Cheng Y.Y., Pels E., Nuijts R.M. Femtosecond-laser-assisted Descemet’s stripping endothelial keratoplasty. J. Cataract Refract. Surg., 2007, vol. 33, pp. 152-155. 34. Jones Y.J., Goins K.M., Sutphin J.E., Mullins R., Skeie J.M. Comparison of the femtosecond laser (IntraLase) versus manual microkeratome (Moria ALTK) in dissection of the donor in endothelial keratoplasty: initial study in eye bank eyes. Cornea, 2008, vol. 27, no. 1, pp. 88-93. 35. Mootha V.V., Heck E., Verity S.M., Petroll W.M., Lakshman N., Muftuoglu O. et al. Comparative study of Descemet stripping automated endothelial keratoplasty donor preparation by Moria CBm micro keratome, horizon microkeratome, and Intralase FS60. Cornea, 2011, vol. 30, no. 11, pp. 320-324. 36. Sikder S., Snyder R.W. Femtosecond laser preparation of donor tissue from the endothelial side. Cornea, 2006, vol. 25, no. 4, pp. 416-422. 37. Neroev V.V., Gundorova R.A., Stepanov A.V., Bykov V.P., Penkina A.V., Oganesyan O.G. Pervyy opyt i kratkosrochnye rezul'taty femtolazernoy zadney posloynoy keratoplastiki (DSEK) s formirovaniem transplantata s endotelial'noy storony. Rossiyskiy meditsinskiy zhurnal – Medical Journal of the Russian Federation, 2013, no. 5, pp. 44-46.



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